mediclore - A Randomized Controlled Trial of ThermoSensitive mgcl SolGel AntiAdhesion PDF Antiadhesive effect and safety of a thermosensitive adhesion barrier Mediclore Cgbio En Mediclore is an adhesion barrier composed of biocompatible and watersoluble hydrophilic polymer that transits from Sol to Gel Mediclore prevents postoperative adhesion formation to an adjacent tissue or organ by providing surface lubricity Mediclore is a solgel agent that becomes a gel when applied to the surgical site and prevents postoperative adhesions A randomized controlled trial evaluated its antiadhesive effect and safety for thyroidectomy patients but did not show significant improvement Clinical Results of Antiadhesion Adjuvants after Endonasal PDF Antiadhesive effect and safety of a ResearchGate Antiadhesive effect and safety of a thermosensitive adhesion barrier MEDICLORE in Adhesion and Thyroidectomy ICH GCP Mediclore is a mixture of watersoluble polymeric composites contained in a singleuse prefilled sterile 5 mL syringes In the experimental group 5 mL of Mediclore was applied evenly throughout the surgical site just before wound closure Adept is a colorless nonviscous isoosmolar 4 solution of icodextrin The investigators planned double blind prospective study of Thermosensitive Adhesion Barrier MEDICLORE to reveal antiadhesive effect of MEDICLORE The investigators will recruit total 90 patients control group 45 experimental group 45 and compare postoperative outcomes about adhesion Study Overview Status Mediclore Daewoong Indonesia Antiadhesive effect and safety of a thermosensitive adhesion barrier of Mediclore have been reported in various studies 9122122 In this study swallowing di magdalenka fficulty and wrink le problems were the most severe at 2 w eek s after thyroid surgery and Mediclore composed of poloxamer gelatin and chitosan is a temperaturedependent solgel antiadhesion product The product is easily injectable at room temperature and is considered to have greater adhesion strength that can withstand gravity because of its solgel characteristics compared to GuardixSol which is a soltype barrier This study used an antiadhesion agent called Mediclore a temperaturesensitive solgel composed of poloxamer gelatin and chitosan Mediclore acts as an external barrier to prevent adhesion until absorbed for approximately 20 days Antiadhesive and antibacterial effects of Mediclore have been reported in various studies 91011122122 Mediclore Giraffe Healthcare Antiadhesive effect and safety of a thermosensitive adhesion barrier Mediclore for thyroid surgery a doubleblinded randomized controlled trial Ann Surg Treat Res 2022 Jun1026313322 doi 104174astr20221026313 Epub 2022 Jun 7 Authors JongHyuk Ahn 1 Mediclore is a dressing for deepcavity wound and it is mainly used to reduce adhesion after spine surgery It is a solgel type solution that becomes a gel when it reaches body temperature and provides a lubricating surface between adjacent tissues or organs Mediclore is a sterile single use polymeric gel mainly used for reducing adhesion after open and laparoscopic procedures Composition Poloxamer Chitosan Indication Against postop adhesion formation to adjacent tissueorgan Add lubricity to areas in need Specification 10ml 12ml 15ml 17ml 20ml kondom kateter 30ml 40ml 50ml syringe
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