mepe - Also because MEPE transgenic MEPE tgn arlott mlbb mice unlike HYP mice express PHEX we induced a dietary hypophosphatemia and hypovitaminosis D to study phosphate and vitamin D effects on MEPE in vivo activity This study shows that MEPE is antiosteogenic inhibits bone resorption modulates serum phosphate suppresses renal calcification and alters MEPE Wikipedia Mepe Is Expressed During Skeletal Development and Regeneration In situ hybridization of Mepe in 3weekold mouse tibiaMepe was found to be abundantly expressed by growth plate chondrocytes and osteoblasts of the metaphysis A Expression was present in both the proliferating zone PZ and the hypertrophic zone HZ of the growth plate as indicated by the arrows B with an apparent increase in expression in the hypertrophic zone of chondrocytes C MEPE matrix extracellular phosphoglycoprotein human MEPE knockout mice have a phenotype of increased bone mass in the femur Gowen et al 2003 Bone marrow cultures from MEPE mutant mice show increased osteoblast number and osteoblast activity Gowen et al 2003 Collectively these studies indicate that MEPE is a bone metabolism regulator and that its primary function might MEPE matrix extracellular phosphoglycoprotein Homo sapiens human MEPE Gene GeneCards MEPE Protein MEPE Antibody The MEPE matrix extracellular phosphoglycoprotein is a proteincoding gene located on chromosome 4 Matrix extracellular phosphoglycoprotein Osteoblastosteocyte factor 45 is a protein encoded by the MEPE gene in humans It contains a conserved RGD motif potentially involved in integrin recognition Matrix Extracellular Phosphoglycoprotein ScienceDirect MEPE or the cemong MEPEderived acidic serine aspartaterich MEPEassociated motif peptide may contribute to decreased bone mineralization in Oncogenic osteomalacia patients Title Matrix extracellular phosphoglycoprotein is expressed in causative tumors of oncogenic osteomalacia MEPE has the properties of an osteoblastic phosphatonin and minhibin MEPE is a gene that encodes a calciumbinding phosphoprotein involved in bone and dentin mineralization Learn about its aliases disorders pathways products expression function localization and more MEPE expression is higher when cells proliferate whereas it is downregulated as cells differentiated MEPE is predominantly expressed by osteocytes in human bone with significant expression by osteocytes within mineralized bone The results are consistent with MEPE being involved in phosphate and bone metabolism in a normal population Learn about MEPE a protein involved in bone mineralization and phosphate homeostasis from various chapters and articles Find out how MEPE is related to osteomalacia osteoarthritis calcinosis and other conditions MEPE Matrix Extracellular Phosphoglycoprotein MEPE Is a New Bone Renal MEPE is a gene that encodes matrix extracellular phosphoglycoprotein a protein with an RGD motif that binds to integrins It is expressed in osteoblasts and osteocytes and regulates phosphate homeostasis and skeletal mineralization MEPE is a novel regulator of growth plate cartilage mineralization MEPE is a secreted RGDmatrix phosphoglycoprotein upregulated in OHO tumors and Hyp osteoblasts Moreover MEPE is exclusively expressed in osteoblasts osteocytes and odontoblasts 2315262962717981 MEPE also belongs to the short integrinbinding ligand interacting glycoprotein SIBLING family that all dekdok map to 4q211 2471
vosco
angka korea sino
