nsmp - Histopathologybased machine learning classifier to differentiate ukuran dari lapangan bola basket adalah NSMP and p53abn ECs Fig 1 depicts our AIbased histopathology image analysis pipeline A subset of 27 wholesection HE slides NSMP Home Refining adjuvant treatment in endometrial cancer based on molecular The NSMPORANGE trial is an international phase III noninferiority trial in which patients with stage II LVSI or stage III NSMP endometrial cancer are randomized 11 to adjuvant radiotherapy followed by progesterone tablets either medroxyprogesterone acetate or megestrol acetate for 2 years or adjuvant chemoradiation alone Abstract Endometrial carcinomas ECs classified by The Cancer Genome Atlas TCGA as copy numberlow also referred to as no specific molecular profile NSMP have a prognosis intermediate between POLEmutated and copy numberhigh ECsNSMPECs are a heterogeneous group however comprising both relatively indolent and aggressive ECs The NSMPORANGE trial is a treatment deescalation trial for women with estrogen receptorpositive Stage II with LVSI or Stage III nonspecific molecular profile NSMP endometrial cancer comparing radiotherapy followed by progestin for 2 years to adjuvant chemoradiation The POLEmutBLUE trial is a Phase 2 trial in which the safety of de Subgroupanalysis showed that only in NSMP HREC ERpositivity was independently associated with a reduced risk of recurrence HR 033 95CI 015075 We confirmed the prognostic impact of Prognostic refinement of NSMP highrisk endometrial cancers using Genomic Landscape of Endometrial Carcinomas of No Specific Molecular The law firm Nurjadin Sumono Mulyadi Partners NSMP has since its establishment in 2006 handled various complex and sophisticated transactions as well as highprofile cases which lelang caready have contributed to NSMPs cumulative expertise and lead to its recognition in both domestic and international markets as well as the legal community as a whole making NSMP one of the most well NSMP owns and develops largescale gas transportation processing and liquefaction assets in and around the North Sea Learn about their ESG and energy transition initiatives and explore their assets Prognostic refinement of NSMP highrisk endometrial cancers using AIbased histopathology image analysis reveals a distinct subset of Nurjadin Sumono Mulyadi Partners Grade and Estrogen Receptor Expression Identify a Subset of No Specific Currently NSMP clear cell carcinomas are excluded from the prognostic risk groups of the European clinical guidelines due to insufficient evidence 17 33 Incorporating ER status of NSMP EC into the prognostic risk groups will decrease the number of patients that cannot be classified Within NSMP EC the lowrisk and highrisk categories were of prognostic significance independent of the stage on a multivariate analysis Lowgrade and ERpositive NSMP ECs are a homogeneous lowrisk group associated with an exceptionally favorable prognosis in which deescalation andor endocrine therapy strategies can be applied Prognostic refinement of NSMP highrisk endometrial cancers using Molecular subtypes of endometrial cancer Implications for adjuvant We confirmed the prognostic impact of the molecular classification age stage and adjuvant CTRT in a large cohort of highrisk EC ERpositivity is a strong favourable prognostic factor in NSMP HREC and identifies a homogeneous subgroup of NSMP tumours Assessment of ER status situs wajak in highrisk NSMP E
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