oksikodon - DailyMed OXYCODONE HYDROCHLORIDE tablet Generic Name jack88 Oxycodone DrugBank Accession Number DB00497 Background Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917 3 It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period OpioidInduced Hyperalgesia and Allodynia OpioidInduced Hyperalgesia OIH occurs when opioid analgesic paradoxically causes an increase in pain or an increase in sensitivity to painIf OIH is suspected carefully consider appropriately decreasing the dose of the current opioid analgesic or opioid rotation The tablets contain the following inactive ingredients magnesium stearate microcrystalline cellulose silicon dioxide and stearic acid The 5 mg tablet also contains DC Red No 30 aluminum lake DC Yellow No 10 aluminum lake and hydrated alumina Oxycodone is a potent semisynthetic opioid with agonistic properties on mu kappa and deltatype opioid receptors This drug is beneficial when used judiciously for pain management yet it carries the risk of inducing physical dependence and addiction The immediaterelease formulation of oxycodone is approved by the US Food and Drug Administration FDA for managing acute or chronic Oxycodone Uses Dosage Side Effects Drugscom Oxycodone StatPearls NCBI Bookshelf Oxycodone sold under the brand name Roxicodone and OxyContin which is the extendedrelease form among others is a semisynthetic opioid used medically for the treatment of moderate to severe painIt is highly addictive 14 and is a commonly abused drug 15 16 It is usually taken by mouth and is available in immediaterelease and controlledrelease m30s formulations 15 Oxycodone 15 Mg TabletOral ONLY Not Feeding Tubes WebMD Oxycodone DEAgov Oxycodone Tablets Package Insert Prescribing Info Drugscom Oxycodone C18H21NO4 CID 5284603 PubChem PharmGKB summary oxycodone pathway pharmacokinetics PMC Oxycodone Wikipedia Background Oxycodone is a semisynthetic opioid derived from thebaine and is an opioidreceptor agonist used to provide analgesia to patients It has been in clinical use since 1917 and is recommended for the treatment of moderate to severe pain although it may not be effective in the treatment of some painful conditions such as diabetic neuropathy Oxycodone is a semisynthetic narcotic analgesic and historically has been a popular drug of abuse among the narcotic abusing population Oxycodone has a risk for abuse and addiction which can lead to overdose and death Oxycodone may also cause severe possibly fatal breathing problemsTo lower your risk your doctor should have Warnings Oxycodone hydrochloride carries several Boxed Warnings for risk of addiction overdose and death serious or fatal respiratory depression fatalities from accidental ingestion by children fatal side effects when used with other respiratory depressants or CYP3A4 inhibitors the risk of Neonatal Opioid Withdrawal syndrome in babies born dependent on oxycodone and the Opioid We evaluated 1014 fatality cases involving oxycodone OXC for evidence of enhanced toxicity associated with multiple drugdrug interactions We previously reported on these cases and we classified them by a standardized method into groups that distinguished cases unrelated to drug abuse from those related to drug abuse cases that involved only OXC from cases involving multiple drugs drug Oxycodone Uses Interactions Mechanism sancai of Action DrugBank Online
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