organofosfat - Organophosphate Poisoning What You Should Know kingled WebMD See also General Principles of Poisoning Some organophosphates were developed as nerve agents for use in warfare One sarin has been used by terrorists Organophosphates and carbamates are commonly used as insecticides see table Symptoms fn Treatment of Specific Poisons Sep 8 2022 Pesticides are composed of chemicals that can be employed to kill pests or minimize their negative effects Pesticides and other organophosphate containing compounds have been beneficial in Organophosphates Toxicity Pathophysiology Diagnosis and Organophosphate poisoning is poisoning due to organophosphates OPs 4 Organophosphates are used as insecticides medications and nerve agents 4 Symptoms include increased saliva and tear production diarrhea vomiting small pupils sweating muscle tremors and confusion 2 Organophosphates as weapons As a weapon organophosphates may be spread through the air It also can be an agent of opportunity This means that someone could explode the vehicle of transportation truck or train that is being used to ship the chemical or destroy tanks that store the chemical Organophosphates are a class of organophosphorus compounds with the general structure OP OR3 a central phosphate molecule with alkyl or aromatic substituents They are widely used as pesticides biomolecules flame retardants and plasticizers and have various synthesis methods and bonding properties Organophosphate poisoning BMJ Best Practice Nov 12 2023 Organophosphates encompass a diverse group of chemical compounds and are formed through esterification between phosphoric acid and alcohol Currently organophosphates have common applications in pesticides and herbicides as well as nerve agents in chemical warfare Therefore most patients exposed Organophosphates Background Pathophysiology Etiology Organophosphate Wikipedia Mar 13 2023 Organophosphate OP compounds are a diverse group of chemicals used in both domestic and industrial settings Examples of organophosphates include insecticides malathion parathion diazinon fenthion dichlorvos chlorpyrifos ethion nerve gases soman sarin tabun VX ophthalmic agents echothiophate isoflurophate and antihelminti Nov 12 2023 Organophosphates encompass a diverse group of chemical compounds and are formed through esterification between phosphoric acid and alcohol Currently organophosphates have common applications in pesticides and herbicides as well as nerve agents in chemical warfare Therefore most patients exposed to organophosphates typically encounter these compounds through the use of insecticides and Sep 27 2024 Organophosphates OPs are chemical substances originally produced by the reaction of alcohols and phosphoric acid In the 1930s organophosphates were used as insecticides but the German military developed these substances as neurotoxins in World War II Management of Organophosphorus Poisoning Critical Care Clinics In many parts of the world particularly in impoverished nations like Ethiopia organophosphate compounds operate as reycle suicide agents are frequently employed as pesticides and are strong inhibitors of the acetylcholinesterase enzyme A 21yearold Mar 14 2024 Organophosphate poisoning can occur due to occupational or accidental exposure deliberate ingestion or chemical warfare with nerve gases Presentation is highly variable due to differences in dose agent toxicity and type of exposure Organophosphate Toxicity PubMed Organophosphates StatPearls NCBI Bookshelf The typical toxidrome in organophosphate OP poisoning comprises of the Salivation Lacrimation Urination Defecation Gastric cramps Emesis SLUDGE symptoms However several other manifestations are described We review the spectrum of Poisoning by Organophosphate Pesticides A Case Report PMC Zebrafish as a platform for in vivo drug discovery Randall T Peterson Calum A MacRae in Drug Discovery Today Disease Models 2013 Organophosphates Organophosphates are small molecule acetylcholinesterase inhibitors used as pesticides and as nerve agents for chemical warfare 3638 Organophosphate Poisoning What It Is Symptoms Treatment Clinical features of organophosphate poisoning A review of Mechanisms of organophosphate neurotoxicity PMC Organophosphate Toxicity Practice Essentials Background Organophosphorus OP compounds remain a leading cause of selfpoisoning and mortality especially in South East Asia China and Africa Organophosphorus causes an acute cholinergic syndrome by inhibiting acetylcholinesterase Atropine remains the mainstay of treatment but recently some promising therapies are in the pipeline Oximes are used widely in the management of organophosphorus Organophosphate Toxicity StatPearls NCBI Bookshelf Abstract The canonical mechanism of organophosphate OP neurotoxicity is the inhibition of acetylcholinesterase AChE However multiple lines of evidence suggest that mechanisms in addition to or other than AChE inhibition contribute to the neurotoxic effects associated with acute and chronic OP exposures Organophosphate Toxicity Clinical Presentation Medscape Nov 12 2023 Organophosphates are chemical compounds formed through the esterification process involving phosphoric acid and alcohol These chemicals serve as primary components in herbicides pesticides and insecticides and have extensive application in manufacturing plastics and solvents Organophosphates can undergo hydrolysis and release alcohol from the ester bond Organophosphates are also the Organophosphate an overview ScienceDirect Topics Organophosphate Poisoning and Carbamate Poisoning Jul 18 2024 Organophosphate poisoning is the harmful effects of exposure to certain compounds found in agricultural products or chemical warfare agents ORGANOPHOSPHATES idphstateilus Feb 13 2024 Organophosphate poisoning can cause serious breathing problems Learn more about this condition what causes it symptoms and your treatment options Organophosphate poisoning Wikipedia Organophosphate OP compounds are a diverse group of chemicals used in both domestic and industrial settings Examples of organophosphates include insecticides malathion parathion diazinon fenthion dichlorvos chlorpyrifos ethion nerve gases soman sarin tabun VX ophthalmic agents kuda138 echothiophate isoflurophate and antihelminti
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