primojel - Primojel is a product of DFE flagyl PHARMA that can enhance disintegration and dissolution of tablets and capsules It has exceptional swelling performance robust functionality and meets various quality standards Primojel is used only in the extragranular phase If lactose is used instead of dibasic calcium phosphate then the effect of Primojel location is greatly reduced In direct compression The recommended starting point is 2ww to 4ww of Primojel The figure shows how the disintegration time of various placebo tablets 250 mg 9 mm tablets Primojel takes up more than 20 times its own weight of water Rapid water penetration into the tablets and powerful swelling results in rapid disintegration Studies show that Primojel takes up more water than comparative products on the market and develops a strong disintegrating force making it a highly effective product The botanical source degree of crosslinking and degree of PDF Oral Solid Dose TECHNICAL PAPER OF SUPERDISINTEGRANTS DFE Pharma The swelling action makes Primojel most effective in nonsoluble matrices With soluble or partially soluble matrix components the matrix is dissolving and thus the disintegrant is deprived of some of what it might push against thus reducing the disintegrant effect Moreton 2008 Croscarmellose sodium Primellose Primojel sodium starch glycolate is a superdisintegrant suitable for various tablet and capsule formulations In higher concentrations Primojel can act as a dissolution enhancing agent Primojel is highly effective when used intragranular andor extragranular in drywet granulation processes Primojel Pharma Excipients Superdisintegrants and their working mechanisms by DFE Pharma Primojel Sodium starch glycolate is a superdisintegrant suitable for ifxtrade a variety of tablet and capsule formulations In higher concentrations Primojel can act as a dissolution enhancing agent Primojel is highly effective when used intragranular andor extragranular in granular formulations Size Drum 50kg Variant sold out or unavailable Learn about the chemistry synthesis properties and applications of sodium starch glycolate SSG a widely used excipient in pharmaceutical tablets and capsules SSG is available from different manufacturers under trade names such as Primojel Explotab and Vivastar Sodium Starch Glycolate as a Superdisintegrant Review Article DFE Pharma Excipients Primojel Sodium Starch Glycolate Primojel sodium starch glycolate is a super disintegrant suitable for various tablet and capsule formulations In higher concentrations Primojel can act as a dissolution enhancing agent Primojel is highly effective when used intragranular andor extra granular in drywet granulation processes Primojel Sodium starch glycolate from DFE Pharma Primojel is a superdisintegrant made from crosslinked and carboxymethylated potato starch It is suitable for direct compression dry granulation wet granulation and dry blending of tablets and capsules IMCD Leading Speciality Chemicals Ingredients Distributor Primojel DFE Pharma CPHI Online PDF Oral Solid Dose Primojel DFE Pharma Primojel DFE Pharma Estore Primojel Primellose 0 5 10 100 60 80 40 20 0 Particle size ww 63 micron 75 micron 125 micron 0 5 10 10 6 8 4 2 0 Moisture LOD ww 0 5 10 1 06 08 04 02 0 Degree of substitution 0 5 10 40 20 30 10 0 Settling volume ml Figure 7 Consistency of functional related characteristic of Primojel delizioso top and Primellose bottom
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