siscom - Oct 26 2009 Dr Gregory Cascino cacing sutra a Mayo Clinic neurologist and epileptologist describes SISCOM an advanced imaging technology developed at Mayo Clinic Visit httpmay On the optimal z score threshold for SISCOM analysis to SISCOM at Mayo Clinic YouTube Subtraction Ictal SPECT coregistered to MRI SISCOM as a Sep 6 2016 Subtraction of interictal from ictal SPECT coregistered to 3dimensional MRI SISCOM is an improved and better validated technique for ictal and interictal SPECT subtraction Various clinical studies have been performed using this SISCOM technique in the field of epilepsy OBrien et al 1998a b 1999 Lee et al 2000 SISCOM was able to localize the PEZ in 510 2651 and to additionally lateralize the PEZ in 176 951 achieving better localizations than ictal SPECT FDGPET and MRI P 01 SISCOM was useful to localize the PEZ in 25 of patients with poorly localizing videoEEG and in 278 of MRInegative cases Subtraction Ictal SPECT coregistered to MRI SISCOM as a Imaging epilepsy with SISCOM Marino M Bianchin Lauro WichertAna Tonicarlo R Velasco Ana Paula P Martins and Américo C Sakamoto We read with interest the Review by Duncan Clinical Usefulness of SISCOMSPM Compared to Visual Analysis The role of SISCOM in preoperative evaluation for patients Apr 17 2018 The accuracy of SISCOM in the localization has been assessed by several studies comparing SISCOM with invasive ictal EEG surgical site or combined modalities 46 Moreover SISCOM elevates the predictive value of the surgical workup procedure to preoperatively estimate chances of good surgical outcome 710 Therefore SISCOM is a Oct 11 2020 The sensitivity of ictal SPECT is high in temporal lobe epilepsy but relatively lower in extratemporal epilepsy SISCOM is an imaging technique to subtract ictal and interictal SPECT images and to coregister them on brain MRI SISCOM significantly improves the sensitivity of ictal SPECT and can further localize epileptic focus May 1 2016 35 Objectives Ictalinterictal subtraction SPECT with coregistration to MRI provides a valuable noninvasive method to locate seizureonset zone Both conventional subtraction methods eg SISCOM and statistical parametric mapping SPMbased methods eg STATISCOM have been employed to aid epilepsy presurgical workup Among them SPM methods accounting for normal variation between two Imaging epilepsy with SISCOM Nature Reviews Neurology SISCOM is a highly valuable diagnostic tool to localize the seizureonset zone in nonlesional and extratemporal epilepsies Outcome in this patient group was unexpectedly good even in patients with nonlesional MRI The high correlation with ECoG and site of successful surgery is a strong indicator MNI SISCOM is a new free and opensource software application for computing SISCOM and producing practical MRISPECTSISCOM image panels for review and reporting The graphical interface allows any user to quickly and easily obtain SISCOM images with minimal user interaction MNI SISCOM an OpenSource Tool for Computing Subtraction Our results using SISCOMSPM agree with the studies that demonstrated an improvement in EZ detection using SISCOM without SPM In our study SISCOMSPM showed a higher sensitivity chawarin compared to visual analysis 783 vs 565 respectively and provided a 218 increase in the EZ localization which can be valuable in clinical practice MNI SISCOM an OpenSource Tool for Computing Subtraction Frontiers Clinical Usefulness of SISCOMSPM Compared to Comparison of SISCOM STATISCOM and MIMneuro for seizure SISCOM Subtraction Ictal SPECT Coregistered to MRI Jul 18 2020 In 142 MRInegative patients the SISCOM positive rate was 838 The pooled PPV of 178 surgical patients with concordant SISCOM was 56 In the metaanalysis of 275 surgical patients the seizurefree odds ratio was 328times higher in concordant than in nonconcordant SISCOM patients 95CI 190 567 Of Blobs and Buzzes Does SISCOM Imaging Actually Help SEEG Prospective use of subtraction ictal SPECT coregistered to Mar 12 2016 SISCOM could provide more complementary information together with other conventional measurements Furthermore SISCOM evaluation has a moderate PPV for good postoperative outcomes This is the first metaanalysis of SISCOM and our data further confirm that the localizing results of SISCOM could be a valuable indicator for seizurefree outcomes Imaging epilepsy with SISCOM Nature Feb 18 2021 Subtraction ictal singlephoton emission computed tomography SPECT coregistered to MRI SISCOM is a wellestablished technique for quantitative analysis of ictal vs interictal SPECT images that can contribute to the identification of the seizure onset zone in patients with drugresistant epilepsy However there is presently a lack of userfriendly free and opensource software to compute The role of SISCOM in preoperative evaluation for patients Dec 26 2019 SISCOM was useful to localize the PEZ in 25 of patients with poorly localizing videoEEG and in 278 of MRInegative cases The occurrence of habitual seizures during injection for ictal SPECT and the temporal localization of the PEZ both correlated with a better SISCOM localization P 05 364 1644 patients were finally selected for Apr 6 2011 The use of SISCOM might improve the presurgical evaluation of patients with temporal lobe epilepsy 111213 and might be particularly useful for preoperative assessment of patients with Oct 1 2016 SISCOM is a technique that subtracts ictal and interictal SPECT images and coregisters them to MRI This article reviews the literature on SISCOMs sensitivity specificity concordance and predictive value for seizure localization and surgical outcomes in epilepsy patients SISCOM Subtraction Ictal SPECT with Coregistration to MRI The role of SISCOM in preoperative evaluation for patients SISCOM hyperperfusion can indicate areas of ictal spread andor high functional connectivity to the IOZ Subtraction ictal SPECT coregistered to MRIdirected SEEG planning allows more complete electrographic sampling of salient areas which may help us better define specific SEEG power fingerprints to differentiate areas of ictal onset May 28 2020 Our results using SISCOMSPM agree with the studies that demonstrated an improvement in EZ detection using SISCOM without SPM In our study SISCOMSPM showed a higher sensitivity compared to visual analysis 783 vs 565 respectively and provided a 218 increase in the EZ localization which can be stabile valuable in clinical practice
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